The Use of Natural Products Against Fusarium oxysporum: A Review

Zeyneb       Belhi; Noureddine       Boulenouar; Abdelkrim       Cheriti
Abstract

Currently, numerous researchers have focused their attention on the use of natural products from plants and microorganisms, or compounds derived from these organisms to protect crops from various diseases, thus reducing the negative effects on human health and environmental safety. Fungal diseases cause a considerable loss of crop yields in agricultural industries worldwide. Fusarium oxysporum comprises a multitude of formae speciales that cause vascular wilt diseases of economically important crops. This review presents an overview of researches realized on natural products tested against Fusarium oxysporum formae speciales phytopathogens for the period (2017-2020). This review aimed to collect major research works of the antifungal compounds against these fungi and updates information on their developments and approaches that have been rapidly taking place in recent years so that further novel researches can be envisaged. This review discussed these studies by analyzing different sources for antifusariosis treatment, evaluation of testing methods, and information on their advantages and limitations and determined those with real efficacy. Despite the important number of natural products with remarkable in vitro efficiency, the limiting point is their in vivo application for soil microorganisms (in this case: Fusarium oxysporum). Therefore, more advanced researches are needed to solve this problem.
Keywords: Antifungal activity, Fusarium oxysporum), natural products, bioactive compounds, antifungal techniques, plant disease, crops.
Graphical Abstract

[1] 
Davari, M.; Ezazi, R. 
            Chemical composition and antifungal activity of the essential oil of Zhumeria majdae, Heracleum persicum and  Eucalyptus sp. against some important phytopathogenic fungi.
           J. Mycol. Med.,  2017, 27(4), 463-468.
[http://dx.doi.org/10.1016/j.mycmed.2017.06.001] [PMID: 28757068] 
[2] 
Mahlo, S.M.; Chauke, H.R.; McGaw, L.; Eloff, J. Antioxidant and antifungal activity of selected medicinal plant extracts against phytopathogenic fungi. Afr. J. Tradit. Complement. Altern. Med.,  2016, 13(4), 216-222.
[http://dx.doi.org/10.21010/ajtcam.v13i4.28] [PMID: 28852739] 
[3] 
Al-Asmari, F.; Mereddy, R.; Sultanbawa, Y. A novel photosensitization treatment for the inactivation of fungal spores and cells mediated by curcumin. J. Photochem. Photobiol. B,  2017, 173, 301-306.
[http://dx.doi.org/10.1016/j.jphotobiol.2017.06.009] [PMID: 28623822] 
[4] 
Zhao, Y-M.; Cheng, Y-X.; Ma, Y-N.; Chen, C-J.; Xu, F-R.; Dong, X. 
            Role of phenolic acids from the rhizosphere soils of 
            
              Panax notoginseng
            
             as a double-edge sword in the occurrence of root-rot disease.
           Molecules,  2018, 23(4), 819.
[http://dx.doi.org/10.3390/molecules23040819] [PMID: 29614031] 
[5] 
Prieto, J. A.; Patiño, O. J.; Plazas, E. A.; Pabón, L. C.; Ávila, M. C.; Guzmán, J. D.; Delgado, W. A.; Cuca, L. E. Natural products from plants as potential source agents for controlling Fusarium. Fungicides-Showcases of Integrated Plant Disease Management from Around the World.  Croacia: Intech,  2013, 233-278.
[6] 
Confortin, T.C.; Todero, I.; Soares, J.F.; Luft, L.; Brun, T.; Rabuske, J.E.; Nogueira, C.U.; Mazutti, M.A.; Zabot, G.L.; Tres, M.V. 
            Extracts from
            
               Lupinus albescens
            
            : antioxidant power and antifungal activity 
            
              in vitro
            
             against phytopathogenic fungi.
           Environ. Technol.,  2019, 40(13), 1668-1675.
[http://dx.doi.org/10.1080/09593330.2018.1427800] [PMID: 29336227] 
[7] 
Bartmańska, A.; Wałecka-Zacharska, E.; Tronina, T.; Popłoński, J.; Sordon, S.; Brzezowska, E.; Bania, J.; Huszcza, E. 
            Antimicrobial properties of 
            
              Spent Hops
            
             extracts, flavonoids isolated therefrom, and their derivatives.
           Molecules,  2018, 23(8), 2059.
[http://dx.doi.org/10.3390/molecules23082059] [PMID: 30126093] 
[8] 
Singh, M.K.; Pandey, A.; Sawarkar, H.; Gupta, A.; Gidwani, B.; Dhongade, H.; Tripathi, D.K. 
            Methanolic extract of 
            
              Plumbago Zeylanica-
            
            a remarkable antibacterial agent against many human and agricultural pathogens.
           J. Pharmacopuncture,  2017, 20(1), 18-22.
[http://dx.doi.org/10.3831/KPI.2017.20.004] [PMID: 28392958] 
[9] 
Galletti, J.; Tobaldini-Valerio, F.K.; Silva, S.; Kioshima, É.S.; Trierveiler-Pereira, L.; Bruschi, M.; Negri, M.; Estivalet Svidzinski, T.I. 
            Antibiofilm activity of propolis extract on 
            
              Fusarium 
            
            species from onychomycosis.
           Future Microbiol.,  2017, 12(14), 1311-1321.
[http://dx.doi.org/10.2217/fmb-2017-0052] [PMID: 28975806] 
[10] 
Edel-Hermann, V.; Lecomte, C. Current status of Fusarium oxysporum formae speciales and races. Phytopathology,  2019, 109(4), 512-530.
[http://dx.doi.org/10.1094/PHYTO-08-18-0320-RVW] [PMID: 30461350] 
[11] 
Adnan, M.; Alshammari, E.; Ashraf, S.A.; Patel, K.; Lad, K.; Patel, M. 
            Physiological and molecular characterization of biosurfactant producing endophytic fungi 
            
              Xylaria regalis
            
             from the cones of 
            
              Thuja plicata 
            
            as a potent plant growth promoter with its potential application.
           BioMed Res. Int.,  2018, 20187362148
[http://dx.doi.org/10.1155/2018/7362148] [PMID: 29862287] 
[12] 
Agarwal, M.; Dheeman, S.; Dubey, R.C.; Kumar, P.; Maheshwari, D.K.; Bajpai, V.K. 
            Differential antagonistic responses of 
            
              Bacillus pumilus
            
             MSUA3 against 
            
              Rhizoctonia solani
            
             and 
            
              Fusarium oxysporum
            
             causing fungal diseases in 
            
              Fagopyrum esculentum
            
             Moench.
           Microbiol. Res.,  2017, 205, 40-47.
[http://dx.doi.org/10.1016/j.micres.2017.08.012] [PMID: 28942843] 
[13] 
Ahmad, Z.; Wu, J.; Chen, L.; Dong, W. 
            Isolated 
            
              Bacillus subtilis
            
             strain 330-2 and its antagonistic genes identified by the removing PCR.
           Sci. Rep.,  2017, 7(1), 1777.
[http://dx.doi.org/10.1038/s41598-017-01940-9] [PMID: 28496135] 
[14] 
Al-Asmari, A.K.; Alamri, M.A.; Almasoudi, A.S.; Abbasmanthiri, R.; Mahfoud, M. 
            Evaluation of the 
            
              in vitro
            
             antimicrobial activity of selected Saudi scorpion venoms tested against multidrug-resistant micro-organisms.
           J. Glob. Antimicrob. Resist.,  2017, 10, 14-18.
[http://dx.doi.org/10.1016/j.jgar.2017.03.008] [PMID: 28587870] 
[15] 
Carvalho, C.R.; Ferreira-D’Silva, A.; Wedge, D.E.; Cantrell, C.L.; Rosa, L.H. Antifungal activities of Cytochalasins produced by Diaporthe miriciae, An endophytic fungus associated with tropical medicinal plants. Can. J. Microbiol.,  2018, 64(11), 835-843.
[http://dx.doi.org/10.1139/cjm-2018-0131] [PMID: 29874477] 
[16] 
Kälvö, D.; Menkis, A.; Broberg, A. 
            Secondary metabolites from the root rot biocontrol fungus 
            Phlebiopsis gigantea. Molecules,  2018, 23(6), 1417.
[http://dx.doi.org/10.3390/molecules23061417] [PMID: 29895730] 
[17] 
Ramos, M.V.; Brito, D.; Freitas, C.D.T.; Gonçalves, J.F.C.; Porfirio, C.T.M.N.; Lobo, M.D.P.; Monteiro-Moreira, A.C.O.; Souza, L.A.C.; Fernandes, A.V. Proteomic identification and purification of seed proteins from native Amazonian species displaying antifungal activity. Planta,  2018, 248(1), 197-209.
[http://dx.doi.org/10.1007/s00425-018-2893-y] [PMID: 29675765] 
[18] 
Sarwar, A.; Hassan, M.N.; Imran, M.; Iqbal, M.; Majeed, S.; Brader, G.; Sessitsch, A.; Hafeez, F.Y. Biocontrol activity of surfactin A purified from Bacillus NH-100 and NH-217 against rice bakanae disease. Microbiol. Res.,  2018, 209, 1-13.
[http://dx.doi.org/10.1016/j.micres.2018.01.006] [PMID: 29580617] 
[19] 
Sarwar, A.; Brader, G.; Corretto, E.; Aleti, G.; Ullah, M.A.; Sessitsch, A.; Hafeez, F.Y. Qualitative analysis of biosurfactants from Bacillus species exhibiting antifungal activity. PLoS One,  2018, 13(6)e0198107
[http://dx.doi.org/10.1371/journal.pone.0198107] [PMID: 29864153] 
[20] 
Schalchli, H.; Hormazábal, E.; Rubilar, O.; Briceño, G.; Mutis, A.; Zocolo, G.J.; Diez, M.C. Production of ligninolytic enzymes and some diffusible antifungal compounds by white-rot fungi using potato solid wastes as the sole nutrient source. J. Appl. Microbiol.,  2017, 123(4), 886-895.
[http://dx.doi.org/10.1111/jam.13542] [PMID: 28718996] 
[21] 
Silva, M.S.; Ribeiro, S.F.; Taveira, G.B.; Rodrigues, R.; Fernandes, K.V.; Carvalho, A.O.; Vasconcelos, I.M.; Mello, E.O.; Gomes, V.M. 
            Application and bioactive properties of CaTI, a trypsin inhibitor from 
            
              Capsicum annuum
            
             seeds: membrane permeabilization, oxidative stress and intracellular target in phytopathogenic fungi cells.
           J. Sci. Food Agric.,  2017, 97(11), 3790-3801.
[http://dx.doi.org/10.1002/jsfa.8243] [PMID: 28139827] 
[22] 
Wu, H.; Liu, T.; Lian, Y.; Wang, W. Two new eremophilenolides from the roots of Ligulariopsis shichuana and their anti-phytopathogenic fungal and antifeedant activities. Nat. Prod. Res.,  2019, 33(10), 1442-1448.
[http://dx.doi.org/10.1080/14786419.2017.1419240] [PMID: 29281920] 
[23] 
Wu, X.; Pang, X-J.; Xu, L-L.; Zhao, T.; Long, X-Y.; Zhang, Q-Y.; Qin, H-L.; Yang, D-F.; Yang, X-L. 
            Two new alkylated furan derivatives with antifungal and antibacterial activities from the plant endophytic fungus 
            
              Emericella
            
             sp. XL029.
           Nat. Prod. Res.,  2018, 32(22), 2625-2631.
[http://dx.doi.org/10.1080/14786419.2017.1374269] [PMID: 28927292] 
[24] 
Wu, Z.; Xie, Z.; Wu, M.; Li, X.; Li, W.; Ding, W.; She, Z.; Li, C. 
            New antimicrobial cyclopentenones from Nigrospora sphaerica Zmt05, a fungus derived from Oxya chinensis thunber.
           J. Agric. Food Chem.,  2018, 66(21), 5368-5372.
[http://dx.doi.org/10.1021/acs.jafc.8b01376] [PMID: 29746771] 
[25] 
Xiong, C.; Li, Q.; Li, S.; Chen, C.; Chen, Z.; Huang, W. 
              In vitro
            
             antimicrobial activities and mechanism of 1-octen-3-ol against food-related bacteria and pathogenic fungi.
           J. Oleo Sci.,  2017, 66(9), 1041-1049.
[http://dx.doi.org/10.5650/jos.ess16196] [PMID: 28794307] 
[26] 
Yuan, C.; Ding, G.; Wang, H-Y.; Guo, Y-H.; Shang, H.; Ma, X-J.; Zou, Z-M. 
            Polyketide-terpene hybrid metabolites from an endolichenic Fungus pestalotiopsissp.
           BioMed Res. Int.,  2017, 20176961928
[http://dx.doi.org/10.1155/2017/6961928] [PMID: 28593175] 
[27] 
Zandvakili, N.; Zamani, M.; Motallebi, M.; Moghaddassi Jahromi, Z. 
            Cloning, overexpression and 
            in vitro
             antifungal activity of 
            zea mays
             pr10 protein.
           Iran. J. Biotechnol.,  2017, 15(1), 42-49.
[http://dx.doi.org/10.15171/ijb.1357] [PMID: 28959351] 
[28] 
Zheng, Y-K.; Miao, C-P.; Chen, H-H.; Huang, F-F.; Xia, Y-M.; Chen, Y-W.; Zhao, L-X. Endophytic fungi harbored in Panax notoginseng: diversity and potential as biological control agents against host plant pathogens of root-rot disease. J. Ginseng Res.,  2017, 41(3), 353-360.
[http://dx.doi.org/10.1016/j.jgr.2016.07.005] [PMID: 28701877] 
[29] 
Chen, X.; Hu, L-F.; Huang, X-S.; Zhao, L-X.; Miao, C-P.; Chen, Y-W.; Xu, L-H.; Han, L.; Li, Y-Q. 
            Isolation and characterization of new phenazine metabolites with antifungal activity against root-rot pathogens of 
            Panax notoginseng
             from 
            Streptomyces. J. Agric. Food Chem.,  2019, 67(41), 11403-11407.
[http://dx.doi.org/10.1021/acs.jafc.9b04191] [PMID: 31509401] 
[30] 
Kamel, N.M.; Abdel-Motaal, F.F.; El-Zayat, S.A. 
            Endophytic fungi from the medicinal herb 
            
              Euphorbia geniculata
            
             as a potential source for bioactive metabolites.
           Arch. Microbiol.,  2020, 202(2), 247-255.
[http://dx.doi.org/10.1007/s00203-019-01740-x] [PMID: 31602502] 
[31] 
Srivastava, A.K.; Pandey, L.K. synthesis of chalcones and nucleosides incorporating [1, 3, 4] oxadiazolenone core and evaluation of their antifungal and antibacterial activities. Curr. Bioact. Compd.,  2019, 15(6), 665-679.
[http://dx.doi.org/10.2174/1573407214666180911130110] 
[32] 
Tao, P.; Wu, C.; Hao, J.; Gao, Y.; He, X.; Li, J.; Shang, S.; Song, Z.; Song, J. Antifungal application of rosin derivatives from renewable pine resin in crop protection. J. Agric. Food Chem.,  2020, 68(14), 4144-4154.
[http://dx.doi.org/10.1021/acs.jafc.0c00562] [PMID: 32191457] 
[33] 
Tarhriz, V.; Eyvazi, S.; Shakeri, E.; Hejazi, M.S.; Dilmaghani, A. 
            Antibacterial and antifungal activity of novel freshwater bacterium 
            
              Tabrizicola aquatica 
            
            as a prominent natural antibiotic available in qurugol lake.
           Pharm. Sci.,  2020, 26(1), 88-92.
[http://dx.doi.org/10.34172/PS.2019.56] 
[34] 
Yoo, S-J.; Weon, H-Y.; Song, J.; Sang, M.K. 
            Effects of 
            
              Chryseobacterium soldanellicola
            
             T16E-39 and 
            
              Bacillus siamensis
            
             T20e-257 on biocontrol against phytophthora blight and bacterial wilt and growth promotion in tomato plants.
           Int. J. Agric. Biol.,  2020, 23(3), 534-540.
[35] 
Bentrad, N.; Gaceb-Terrak, R.; Benmalek, Y.; Rahmania, F. 
            Studies on chemical composition and antimicrobial activities of bioactive molecules from date palm (Phoenix dactylifera L.) pollens and seeds.
           Afr. J. Tradit. Complement. Altern. Med.,  2017, 14(3), 242-256.
[http://dx.doi.org/10.21010/ajtcam.v14i3.26] [PMID: 28480436] 
[36] 
Ghazi, R.; Boulenouar, N.; Cheriti, A.; Reddy, K.; Govender, P. 
            Bioguided fractionation of 
            
              citrullus colocynthis 
            
            extracts and antifungal activity against 
            
              Fusarium oxysporum
            
             f.sp. albedinis.
           Curr. Bioact. Compd.,  2020, 16(3), 302-307.
[http://dx.doi.org/10.2174/1573407214666181001124737] 
[37] 
Belhi, Z.; Boulenouar, N.; Cheriti, A.; Marouf, A. 
            Antifungal and anti-cellulases activity of
            
               Limoniastrum feei
            
             extracts to promote Bayoud disease treatment using bioautography.
           Cogent. Food Agric.,  2020, 6(1), 1726083.
[http://dx.doi.org/10.1080/23311932.2020.1726083] 
[38] 
Bouayad Alam, S.; Dib, M.E.A.; Djabou, N.; Tabti, B.; Gaouar Benyelles, N.; Costa, J.; Muselli, A. 
            Essential oils as biocides for the control of fungal infections and devastating pest (Tuta absoluta) of tomato (Lycopersicon esculentum Mill.).
           Chem. Biodivers.,  2017, 14(7)e1700065
[http://dx.doi.org/10.1002/cbdv.201700065] [PMID: 28422413] 
[39] 
Hsu, L-H.; Wang, H-F.; Sun, P-L.; Hu, F-R.; Chen, Y-L. 
            The antibiotic polymyxin B exhibits novel antifungal activity against
            
               Fusarium 
            
            species.
           Int. J. Antimicrob. Agents,  2017, 49(6), 740-748.
[http://dx.doi.org/10.1016/j.ijantimicag.2017.01.029] [PMID: 28433743] 
[40] 
Lahmar, I.; Belghith, H.; Ben Abdallah, F.; Belghith, K. 
            Nutritional composition and phytochemical, antioxidative, and antifungal activities of 
            
              Pergularia tomentosa 
            
            L.
           BioMed Res. Int.,  2017, 20176903817
[http://dx.doi.org/10.1155/2017/6903817] [PMID: 28409159] 
[41] 
Li, W.; Xiong, P.; Zheng, W.; Zhu, X.; She, Z.; Ding, W.; Li, C. 
            Identification and antifungal activity of compounds from the mangrove endophytic fungus 
            
              Aspergillus clavatus
            
             R7.
           Mar. Drugs,  2017, 15(8), 259.
[http://dx.doi.org/10.3390/md15080259] [PMID: 28825634] 
[42] 
Medina-Romero, Y.M.; Roque-Flores, G.; Macías-Rubalcava, M.L. 
            Volatile organic compounds from endophytic fungi as innovative postharvest control of 
            
              Fusarium oxysporum
            
             in cherry tomato fruits.
           Appl. Microbiol. Biotechnol.,  2017, 101(22), 8209-8222.
[http://dx.doi.org/10.1007/s00253-017-8542-8] [PMID: 28965217] 
[43] 
Montenegro, I.; Madrid, A.; Cuellar, M.; Seeger, M.; Alfaro, J.F.; Besoain, X.; Martínez, J.P.; Ramirez, I.; Olguín, Y.; Valenzuela, M. Biopesticide activity from drimanic compounds to control tomato pathogens. Molecules,  2018, 23(8), 2053.
[http://dx.doi.org/10.3390/molecules23082053] [PMID: 30115841] 
[44] 
Mohamed, M.S.M.; Saleh, A.M.; Abdel-Farid, I.B.; El-Naggar, S.A. 
            Growth, hydrolases and ultrastructure of 
            
              Fusarium oxysporum
            
             as affected by phenolic rich extracts from several xerophytic plants.
           Pestic. Biochem. Physiol.,  2017, 141, 57-64.
[http://dx.doi.org/10.1016/j.pestbp.2016.11.007] [PMID: 28911741] 
[45] 
Yu, S.; Teng, C.; Liang, J.; Song, T.; Dong, L.; Bai, X.; Jin, Y.; Qu, J. 
            Characterization of siderophore produced by Pseudomonas syringae BAF.1 and its inhibitory effects on spore germination and mycelium morphology of 
            
              Fusarium oxysporum
            
            .
           J. Microbiol.,  2017, 55(11), 877-884.
[http://dx.doi.org/10.1007/s12275-017-7191-z] [PMID: 29076072] 
[46] 
Zehra, A.; Meena, M.; Dubey, M.K.; Aamir, M.; Upadhyay, R.S. 
            Synergistic effects of plant defense elicitors and 
            
              Trichoderma harzianum
            
             on enhanced induction of antioxidant defense system in tomato against 
            
              Fusarium wilt
            
             disease.
           Bot. Stud. (Taipei, Taiwan),  2017, 58(1), 44.
[http://dx.doi.org/10.1186/s40529-017-0198-2] [PMID: 29098503] 
[47] 
Zhu, X.; Zhong, Y.; Xie, Z.; Wu, M.; Hu, Z.; Ding, W.; Li, C. 
            Zhong, Y.; Xie, Z.; Wu, M.; Hu, Z.; Ding, W.; Li, C., Fusarihexins A and B: Novel cyclic hexadepsipeptides from the mangrove endophytic fungus
            
               Fusarium 
            
            sp. R5 with antifungal activities.
           Planta Med.,  2018, 84(18), 1355-1362.
[http://dx.doi.org/10.1055/a-0647-7048] [PMID: 29954027] 
[48] 
López-Seijas, J.; García-Fraga, B.; da Silva, A.F.; Sieiro, C. 
            Wine lactic acid bacteria with antimicrobial activity as potential biocontrol agents against 
            
              Fusarium oxysporum
            
             f. sp. lycopersici.
           Agronomy (Basel),  2020, 10(1), 31.
[http://dx.doi.org/10.3390/agronomy10010031] 
[49] 
Kalleli, F.; Ghassen, A.; Ben Salem, I.; Boughalleb-M’hamdi, N.M. 
            hamdi, M. Essential oil from fennel seeds (
            
              Foeniculum vulgare
            
            ) reduces Fusarium wilt of tomato (
            
              Solanum lycopersicon
            
            ).
           Phytopathol. Mediterr.,  2020, 59(1), 63-76.
[50] 
Gao, L.; Han, J.; Liu, H.; Qu, X.; Lu, Z.; Bie, X. 
            Plipastatin and surfactin coproduction by 
            
              Bacillus subtilis
            
             pB2-L and their effects on microorganisms.
           Antonie van Leeuwenhoek,  2017, 110(8), 1007-1018.
[http://dx.doi.org/10.1007/s10482-017-0874-y] [PMID: 28477175] 
[51] 
Han, Y.; Zhao, J.; Zhang, B.; Shen, Q.; Shang, Q.; Li, P. 
            Effect of a novel antifungal peptide P852 on cell morphology and membrane permeability of Fusarium oxysporum. Biochim. Biophys. Acta Biomembr.,  2019, 1861(2), 532-539.
[http://dx.doi.org/10.1016/j.bbamem.2018.10.018] [PMID: 30391317] 
[52] 
Huang, N.; Wang, W.; Yao, Y.; Zhu, F.; Wang, W.; Chang, X. 
            The influence of different concentrations of bio-organic fertilizer on cucumber 
            
              Fusarium wilt
            
             and soil microflora alterations.
           PLoS One,  2017, 12(2)e0171490
[http://dx.doi.org/10.1371/journal.pone.0171490] [PMID: 28166302] 
[53] 
Limbadri, S.; Luo, X.; Lin, X.; Liao, S.; Wang, J.; Zhou, X.; Yang, B.; Liu, Y. Bioactive novel indole alkaloids and steroids from deep sea-derived fungus Aspergillus fumigatus SCSIO 41012. Molecules,  2018, 23(9), 2379.
[http://dx.doi.org/10.3390/molecules23092379] [PMID: 30231470] 
[54] 
Wang, Y.; Zhang, J.; Sun, Y.; Feng, J.; Zhang, X. Evaluating the potential value of natural product cuminic acid against plant pathogenic fungi in cucumber. Molecules,  2017, 22(11), 1914.
[http://dx.doi.org/10.3390/molecules22111914] [PMID: 29113138] 
[55] 
Zhang, J.; Tan, W.; Zhang, Z.; Song, Y.; Li, Q.; Dong, F.; Guo, Z. Synthesis, characterization, and the antifungal activity of chitosan derivatives containing urea groups. Int. J. Biol. Macromol.,  2018, 109, 1061-1067.
[http://dx.doi.org/10.1016/j.ijbiomac.2017.11.092] [PMID: 29155157] 
[56] 
Kim, D-R.; Jeon, C-W.; Shin, J-H.; Weller, D.M.; Thomashow, L.; Kwak, Y-S. 
            Function and distribution of a lantipeptide in strawberry 
            
              fusarium wilt
            
             disease-suppressive soils.
           Mol. Plant Microbe Interact.,  2019, 32(3), 306-312.
[http://dx.doi.org/10.1094/MPMI-05-18-0129-R] [PMID: 30256170] 
[57] 
Park, J.Y.; Kim, S.H.; Kim, N.H.; Lee, S.W.; Jeun, Y-C.; Hong, J.K. 
            Differential inhibitory activities of four plant essential oils on 
            
              in vitro
            
             growth of 
            
              Fusarium oxysporum 
            
            f. sp. fragariae causing Fusarium wilt in strawberry plants.
           Plant Pathol. J.,  2017, 33(6), 582-588.
[http://dx.doi.org/10.5423/PPJ.OA.06.2017.0133] [PMID: 29238281] 
[58] 
Mihalache, G.; Balaes, T.; Gostin, I.; Stefan, M.; Coutte, F.; Krier, F. 
            Lipopeptides produced by
            
               Bacillus subtilis 
            
            as new biocontrol products against fusariosis in ornamental plants.
           Environ. Sci. Pollut. Res. Int.,  2018, 25(30), 29784-29793.
[http://dx.doi.org/10.1007/s11356-017-9162-7] [PMID: 28528498] 
[59] 
Patiño, B.; Vázquez, C.; Manning, J.M.; Roncero, M.I.G.; Córdoba-Cañero, D.; Di Pietro, A.; Martínez-Del-Pozo, Á. 
            Characterization of a novel cysteine-rich antifungal protein from
            
               Fusarium graminearum 
            
            with activity against maize fungal pathogens.
           Int. J. Food Microbiol.,  2018, 283, 45-51.
[http://dx.doi.org/10.1016/j.ijfoodmicro.2018.06.017] [PMID: 30099994] 
[60] 
S, X.; L, K.; F, N. S, X.; L, K.; F, N. Effects of different hydroponic substrate combinations and watering regimes on physiological and anti-fungal properties of Siphonochilus aethiopicus. Afr. J. Tradit. Complement. Altern. Med.,  2017, 14(3), 89-104.
[http://dx.doi.org/10.21010/ajtcam.v14i3.10] [PMID: 28480420] 
[61] 
Roşca-Casian, O.; Mircea, C.; Vlase, L.; Gheldiu, A-M.; Teuca, D.T.; Pârvu, M. Chemical composition and antifungal activity of Hedera helix leaf ethanolic extract. Acta Biol. Hung.,  2017, 68(2), 196-207.
[http://dx.doi.org/10.1556/018.68.2017.2.7] [PMID: 28605982] 
[62] 
Sen, S.; Borah, S.N.; Bora, A.; Deka, S. 
            Production, characterization, and antifungal activity of a biosurfactant produced by 
            
              Rhodotorula babjevae
            
             YS3.
           Microb. Cell Fact.,  2017, 16(1), 95.
[http://dx.doi.org/10.1186/s12934-017-0711-z] [PMID: 28558761] 
[63] 
Chen, Y.; Tan, W.; Li, Q.; Dong, F.; Gu, G.; Guo, Z. Synthesis of inulin derivatives with quaternary phosphonium salts and their antifungal activity. Int. J. Biol. Macromol.,  2018, 113, 1273-1278.
[http://dx.doi.org/10.1016/j.ijbiomac.2018.03.055] [PMID: 29548915] 
[64] 
Sun, Y.; Wang, Y.; Han, L.R.; Zhang, X.; Feng, J.T. 
            Antifungal activity and action mode of cuminic acid from the seeds of 
            
              Cuminum cyminum
            
             L. against 
            
              Fusarium oxysporum
            
             f. sp. Niveum (FON) causing 
            
              Fusarium Wilt
            
             on watermelon.
           Molecules,  2017, 22(12), 2053.
[http://dx.doi.org/10.3390/molecules22122053] [PMID: 29189726] 
[65] 
Tan, W.; Zhang, J.; Luan, F.; Wei, L.; Chen, Y.; Dong, F.; Li, Q.; Guo, Z. Design, synthesis of novel chitosan derivatives bearing quaternary phosphonium salts and evaluation of antifungal activity. Int. J. Biol. Macromol.,  2017, 102, 704-711.
[http://dx.doi.org/10.1016/j.ijbiomac.2017.04.073] [PMID: 28445700] 
[66] 
Tan, W.; Li, Q.; Dong, F.; Chen, Q.; Guo, Z. Preparation and characterization of novel cationic chitosan derivatives bearing quaternary ammonium and phosphonium salts and assessment of their antifungal properties. Molecules,  2017, 22(9), 1438.
[http://dx.doi.org/10.3390/molecules22091438] [PMID: 28858241] 
[67] 
Tan, W.; Zhang, J.; Mi, Y.; Dong, F.; Li, Q.; Guo, Z. Synthesis, characterization, and evaluation of antifungal and antioxidant properties of cationic chitosan derivative via azide-alkyne click reaction. Int. J. Biol. Macromol.,  2018, 120(Pt A), 318-324.
[http://dx.doi.org/10.1016/j.ijbiomac.2018.08.111] [PMID: 30144549] 
[68] 
Zhang, M.; Ge, J.; Yu, X. 
            Transcriptome analysis reveals the mechanism of fungicidal of thymol against 
            
              Fusarium oxysporum
            
             f. sp. niveum.
           Curr. Microbiol.,  2018, 75(4), 410-419.
[http://dx.doi.org/10.1007/s00284-017-1396-6] [PMID: 29150703] 
[69] 
Zheng, G.; Luo, S.; Li, S.; Hua, J.; Li, W.; Li, S. 
            Specialized metabolites from 
            
              Ageratina adenophora
            
             and their inhibitory activities against pathogenic fungi.
           Phytochemistry,  2018, 148, 57-62.
[http://dx.doi.org/10.1016/j.phytochem.2018.01.013] [PMID: 29421511] 
[70] 
Xu, X.; Han, L.; Zhao, L.; Chen, X.; Miao, C.; Hu, L.; Huang, X.; Chen, Y.; Li, Y. Echinosporin antibiotics isolated from Amycolatopsis strain and their antifungal activity against root-rot pathogens of the Panax notoginseng. Folia Microbiol. (Praha),  2019, 64(2), 171-175.
[http://dx.doi.org/10.1007/s12223-018-0642-z] [PMID: 30117099] 
[71] 
Zhao, Q.; Chen, L.; Dong, K.; Dong, Y.; Xiao, J. 
            Cinnamic acid inhibited growth of faba bean and promoted the incidence of 
            
              Fusarium wilt
            
            .
           Plants,  2018, 7(4), 84.
[http://dx.doi.org/10.3390/plants7040084] [PMID: 30314266] 
[72] 
Bashir, M.R.; Atiq, M.; Sajid, M.; Mohsan, M.; Abbas, W.; Alam, M.W.; Bashair, M. 
            Antifungal exploitation of fungicides against 
            
              Fusarium oxysporum 
            
            f. sp. capsici causing 
            
              Fusarium wilt 
            
            of chilli pepper in Pakistan.
           Environ. Sci. Pollut. Res. Int.,  2018, 25(7), 6797-6801.
[http://dx.doi.org/10.1007/s11356-017-1032-9] [PMID: 29264855] 
[73] 
Bouzoumita, A.; Metoui, M.; Jemni, M.; Kabaeir, N.; Belhouchette, K.; Ferchichi, A. The efficacy of various bacterial organisms for biocontrol of Fusarium root rot of olive in tunisia. Pol. J. Environ. Stud.,  2020, 29(1), 11-16.
[http://dx.doi.org/10.15244/pjoes/89988] 
[74] 
Lastochkina, O.; Baymiev, A.; Shayahmetova, A.; Garshina, D.; Koryakov, I.; Shpirnaya, I.; Pusenkova, L.; Mardanshin, I.; Kasnak, C.; Palamutoglu, R. 
            Effects of endophytic bacillus subtilis and salicylic acid on postharvest diseases (Phytophthora infestans, Fusarium oxysporum) development in stored potato tubers.
           Plants,  2020, 9(1), 76.
[http://dx.doi.org/10.3390/plants9010076] [PMID: 31936027] 
[75] 
Akhtar, R.; Javaid, A.; Qureshi, M. 
            Bioactive constituents of shoot extracts of 
            
              Sisymbrium irio L.
            
             against 
            
              Fusarium oxysporum 
            
            f. sp. cepae.
           Planta Daninha,  2020, 38
[http://dx.doi.org/10.1590/s0100-83582020380100008] 
[76] 
Rodríguez-Ortiz, R.; Michielse, C.; Rep, M.; Limón, M.C.; Avalos, J. 
            Genetic basis of carotenoid overproduction in 
            
              Fusarium oxysporum.
             Fungal Genet. Biol.,  2012, 49(9), 684-696.
[http://dx.doi.org/10.1016/j.fgb.2012.06.007] [PMID: 22750191] 
[77] 
El Hadrami, I.; El Bellaj, M.; El Idrissi, A. Biotechnologies végétales et amélioration du palmier dattier (Phoenix dactylifera L.), pivot de l’agriculture oasienne marocaine. Cah. Agric.,  1998, 7(6), 463-468.
[78] 
Agrios, G.N. Plant Pathology, 5th ed; Elsevier Academia Press: San Diego Calf. USA, 2005. 
[79] 
Armstrong, G.; Armstrong, J.K. 
            Another approach to race classification of 
            
              Fusarium oxysporum
            
             f. sp. pisi.
           Phytopathology,  1981, 71, 474-478.
[http://dx.doi.org/10.1094/Phyto-71-474] 
[80] 
Armitage, A.D.; Taylor, A.; Sobczyk, M.K.; Baxter, L.; Greenfield, B.P.J.; Bates, H.J.; Wilson, F.; Jackson, A.C.; Ott, S.; Harrison, R.J.; Clarkson, J.P. 
            Characterisation of pathogen-specific regions and novel effector candidates in 
            
              Fusarium oxysporum 
            
            f. sp. cepae.
           Sci. Rep.,  2018, 8(1), 13530.
[http://dx.doi.org/10.1038/s41598-018-30335-7] [PMID: 30202022] 
[81] 
Nirmaladevi, D.; Venkataramana, M.; Srivastava, R.K.; Uppalapati, S.R.; Gupta, V.K.; Yli-Mattila, T.; Clement Tsui, K.M.; Srinivas, C.; Niranjana, S.R.; Chandra, N.S. 
            Molecular phylogeny, pathogenicity and toxigenicity of 
            
              Fusarium oxysporum
            
             f. sp. lycopersici.
           Sci. Rep.,  2016, 6, 21367.
[http://dx.doi.org/10.1038/srep21367] [PMID: 26883288] 
[82] 
Ortiz, E.; Gurrola, G.B.; Schwartz, E.F.; Possani, L.D. Scorpion venom components as potential candidates for drug development. Toxicon,  2015, 93, 125-135.
[http://dx.doi.org/10.1016/j.toxicon.2014.11.233] [PMID: 25432067] 
[83] 
Alajmi, R.; Al-ghamdi, S.; Barakat, I.; Mahmoud, A.; Abdon, N.; Al-Ahidib, M.; Abdel-Gaber, R. 
            Antimicrobial Activity of Two Novel Venoms from Saudi Arabian Scorpions (Leiurus quinquestriatus
             and Androctonus crassicauda).
           Int. J. Pept. Res. Ther., 2019.
[84] 
Bending, G. The Rhizopshere and its microorganisms. App. Encyclo. Plant Sci.,  2017, 2017, 1123-1129.
[85] 
Alabouvette, C.; Olivain, C.; Migheli, Q.; Steinberg, C. 
            Microbiological control of soil-borne phytopathogenic fungi with special emphasis on wilt-inducing 
            
              Fusarium oxysporum.
             New Phytol.,  2009, 184(3), 529-544.
[http://dx.doi.org/10.1111/j.1469-8137.2009.03014.x] [PMID: 19761494] 
[86] 
Caesar, L.K.; Cech, N.B. Synergy and antagonism in natural product extracts: when 1 + 1 does not equal 2. Nat. Prod. Rep.,  2019, 36(6), 869-888.
[http://dx.doi.org/10.1039/C9NP00011A] [PMID: 31187844] 
[87] 
Balouiri, M.; Sadiki, M.; Ibnsouda, S.K. Methods for in vitro evaluating antimicrobial activity: A review. J. Pharm. Anal.,  2016, 6(2), 71-79.
[http://dx.doi.org/10.1016/j.jpha.2015.11.005] [PMID: 29403965] 
[88] 
Van Dijck, P.; Sjollema, J.; Cammue, B.P.; Lagrou, K.; Berman, J.; d’Enfert, C.; Andes, D.R.; Arendrup, M.C.; Brakhage, A.A.; Calderone, R.; Cantón, E.; Coenye, T.; Cos, P.; Cowen, L.E.; Edgerton, M.; Espinel-Ingroff, A.; Filler, S.G.; Ghannoum, M.; Gow, N.A.R.; Haas, H.; Jabra-Rizk, M.A.; Johnson, E.M.; Lockhart, S.R.; Lopez-Ribot, J.L.; Maertens, J.; Munro, C.A.; Nett, J.E.; Nobile, C.J.; Pfaller, M.A.; Ramage, G.; Sanglard, D.; Sanguinetti, M.; Spriet, I.; Verweij, P.E.; Warris, A.; Wauters, J.; Yeaman, M.R.; Zaat, S.A.J.; Thevissen, K. Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms. Microb. Cell,  2018, 5(7), 300-326.
[http://dx.doi.org/10.15698/mic2018.07.638] [PMID: 29992128] 
[89] 
Mani Chandrika, K.V.S.; Sharma, S. Promising antifungal agents: A minireview. Bioorg. Med. Chem.,  2020, 28(7)115398
[http://dx.doi.org/10.1016/j.bmc.2020.115398] [PMID: 32115335] 
Cite As
The Natural Products Journal

The Use of Natural Products Against Fusarium oxysporum: A Review

Abstract

Graphical Abstract
