Current Cancer Therapy Reviews

Author(s): Floriana Morgillo, Giampaolo Tortora and Fortunato Ciardiello

DOI: 10.2174/157339407782496988

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Mechanisms of Intrinsic and Acquired Resistance to EGFR Inhibitors

Page: [276 - 283] Pages: 8

  • * (Excluding Mailing and Handling)

Abstract

In the last decades the epidermal growth factor receptor (EGFR), which is frequently expressed in a variety of epithelial tumors, has been a major target of molecular anticancer therapy.

Keywords: EGFR, Monoclonal antibody, Tyrosine kinase inhibitor, resistance