Letters in Organic Chemistry

Author(s): Byanca Silva Ferreira, Rafaela Corrêa Silva, Bernardo Araújo Souto and Maurício Silva dos Santos*

DOI: 10.2174/1570178617999200728215322

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Synthesis of Pyrazole-Carboxamides and Pyrazole-Carboxylic Acids Derivatives: Simple Methods to Access Powerful Building Blocks

Page: [335 - 343] Pages: 9

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Abstract

Hybrid systems containing pyrazole moiety show a wide spectrum of biological activities. To access novel hybrids with pyrazole ring, in this work we synthesized twenty pyrazole-carboxylic acids and twenty pyrazole-carboxamides, using simple synthetic methods, to be used as building blocks in the development of new structures.

Keywords: Pyrazole, carboxylic acids, carboxamides, heterocyclic derivatives, synthesis, pyrazole hybrids.