Abstract
Introduction: Acute lower respiratory tract infection (ALRTI) is a major public health
problem that causes significant morbidity and mortality and is the main reason for utilization of
health services among children.
Objective: The study aimed to evaluate the clinical profile, severity pattern, and sociodemographic
risk factors of ALRTI in hospitalized children under the age of five years in two tertiary hospitals in
South East Nigeria.
Materials and Methods: This is a cross-sectional study of children aged two months to five years in
two teaching hospitals in the country. They were evaluated for ALRTI, focusing on their clinical
profile and socio-demographic risk factors.
Results: Two hundred children presented with features of ALRTI, mostly pneumonias and
bronchiolitis. ALRTI occurred throughout the year with a peak in October. The majority had severe
disease and risk factors for severity were infancy, type of ALRTI, presence of comorbidity and lack
of measles vaccination or vitamin A supplementation, and exposure to wood smoke. Fast breathing
was the most sensitive symptom, while breathlessness was the most specific for ALRTI.
Conclusion: Bronchopneumonia and bronchiolitis are the most common ALRTI in under-five age
children with bronchopneumonia occurring in severe forms. Poor breastfeeding, infancy, poor rate of
immunization and exposure to biomass smoke are all risk factors for severity.
Keywords:
Acute lower respiratory infections, bronchiolitis, pneumonia, severity score, socio-demographic risk factors,
breathlessness.
Graphical Abstract
[2]
Sikolia DN, Mwololo K, Cherop H. The prevalence of acute respiratory infections and the associated risk factors: A study of children under five years of age in Kibera Lindi Village, Nairobi, Kenya.J.Nal/. Inst Public Health 2002; 51(1): 67-72.
[3]
Kabra SK. Acute respiratory tract infection (ARTI) Control programGhai Essential Pediatrics. 5th ed. New Delhi: Interprint 2000; pp. 349-50.
[4]
Lal S. Epidemiology of Communicable Diseases and Related National Health Programmes Textbook of Community Medicine 2 nd ed New Delhi: M/s CBS Publishers Distributons. 2011. p. 543
[5]
Park K. Epidemiology of Communicable Diseases Park′s Textbook of Preventive and Social Medicine 21 st ed Jabalpur: M/S Banarsidas Bhanot Publishers. 2011. p. 156
[7]
Goel K, Ahmad S, Agarwal G, Goel P. Vijay Kumar. A cross sectional study on prevalence of acute respiratory infections (ARI) in under-five children of Meerut district, India. J Community Med Health Educ 2012.91000176
[8]
Oyejide CD. Review of epidemiological risk factors affecting the pathogenesis of acute respiratory infections. Niger J Paediatr 1988; 15: 1-9.
[9]
Johnson AWBR. Acute respiratory infectionsPaediatrics and Child Health in Tropical Region. 2nd ed. Owerri African Educational Services 2007; pp. 396-425.
[12]
Simoes EA, Rudan I, Gessner BD, Azziz-Baumgartner E, Zhang JS, et al. Global and regional burden of hospital admissions for severe acute lower respiratory infections in young children in 2010: a systematic analysis. Lancet 2013; 381: 1380-90.
[16]
Prober CG. PneumoniaNelson text book of pediatrics. 16th ed. London: WB Saunders 2000; pp. 761-5.
[23]
Johnson AW. Acute respiratory infections Owerri, African educational services. 2007. p. 396
[25]
Chinawa JM, Aniwada EC, Ugwunna NC, Eze JN, Ndu Ikenna K, Obidike EO. Pattern and prevalence of common pediatric illnesses presenting in a private hospital in Onitsha, south east Nigeria: A comparative analysis. Curr Pediatr Res 2018; 22: 88-94.