[14]
Srivastava, C; Gupta, Y; Irshad, K; Chattopadhaya, P; Sarkar, C; Suri, A 123P Curcumin downregulates FAT1 expression via NFkB in glioblastoma. Annals of Oncology, 2017, 28(suppl_10) , mdx657. 005.
[21]
Park, S.Y.; Piao, Y.; Martinez-Ledesma, E.; Dong, J.; Khan, S.; Mittal, S. Targeting MEK in EGFR amplified glioma stem like cells induces differentiation; AACR, 2019.
[31]
Wen, P.Y.; Touat, M.; Alexander, B.M.; Mellinghoff, I.K.; Ramkissoon, S.; McCluskey, C.S.; Pelton, K.; Haidar, S.; Basu, S.S.; Gaffey, S.C.; Brown, L.E.; Martinez-Ledesma, J.E.; Wu, S.; Kim, J.; Wei, W.; Park, M.A.; Huse, J.T.; Kuhn, J.G.; Rinne, M.L.; Colman, H.; Agar, N.Y.R.; Omuro, A.M.; DeAngelis, L.M.; Gilbert, M.R.; de Groot, J.F.; Cloughesy, T.F.; Chi, A.S.; Roberts, T.M.; Zhao, J.J.; Lee, E.Q.; Nayak, L.; Heath, J.R.; Horky, L.L.; Batchelor, T.T.; Beroukhim, R.; Chang, S.M.; Ligon, A.H.; Dunn, I.F.; Koul, D.; Young, G.S.; Prados, M.D.; Reardon, D.A.; Yung, W.K.A.; Ligon, K.L. Buparlisib in patients with recurrent glioblastoma harboring phosphatidylinositol 3-kinase pathway activation: An open-label, multicenter, multi-arm, phase II trial.
J. Clin. Oncol., 2019,
37(9), 741-750.
[
http://dx.doi.org/10.1200/JCO.18.01207] [PMID:
30715997]
[63]
Kong, X-T; Nguyen, N; Choi, Y; Zhang, G; Nguyen, H; Filka, E Actr-53. Safety And Efficacy Evaluation Of A Phase Ii Study Of Bortezomib In Combination With Temozolomide And Regional Radiation Therapy For Upfront Treatment Of Patients With Newlydiagnosed Glioblastoma Multiforme (gbm). Neuro-Oncology, 2017, 19(suppl_6), vi12-vi.
[72]
Herrlinger, U.; Tzaridis, T.; Mack, F.; Steinbach, J.P.; Schlegel, U.; Sabel, M.; Hau, P.; Kortmann, R.D.; Krex, D.; Grauer, O.; Goldbrunner, R.; Schnell, O.; Bähr, O.; Uhl, M.; Seidel, C.; Tabatabai, G.; Kowalski, T.; Ringel, F.; Schmidt-Graf, F.; Suchorska, B.; Brehmer, S.; Weyerbrock, A.; Renovanz, M.; Bullinger, L.; Galldiks, N.; Vajkoczy, P.; Misch, M.; Vatter, H.; Stuplich, M.; Schäfer, N.; Kebir, S.; Weller, J.; Schaub, C.; Stummer, W.; Tonn, J.C.; Simon, M.; Keil, V.C.; Nelles, M.; Urbach, H.; Coenen, M.; Wick, W.; Weller, M.; Fimmers, R.; Schmid, M.; Hattingen, E.; Pietsch, T.; Coch, C.; Glas, M. Neurooncology Working Group of the German Cancer Society. Lomustine-temozolomide combination therapy versus standard temozolomide therapy in patients with newly diagnosed glioblastoma with methylated MGMT promoter (CeTeG/NOA-09): a randomised, open-label, phase 3 trial.
Lancet, 2019,
393(10172), 678-688.
[
http://dx.doi.org/10.1016/S0140-6736(18)31791-4] [PMID:
30782343]
[76]
Aoki, T; Arakawa, Y; Ueba, T; Oda, M; Nishida, N; Akiyama, Y Phase I/II study of temozolomide plus nimustine chemotherapy for recurrent malignant gliomas: Kyoto Neuro-oncology Group. Neurologia medico-chirurgica., 2016, oa. 2016-0162.
[99]
Reardon, D; Omuro, A; Brandes, A; Rieger, J; Wick, A; Sepulveda, J OS10. 3 randomized phase 3 study evaluating the efficacy and safety of nivolumab vs. bevacizumab in patients with recurrent glioblastoma: CheckMate 143. Neuro-oncology, 2017, 19(suppl_3), iii21-iii.
[101]
Sahebjam, S. Forsyth, P; Arrington, J; Jaglal, M; Tran, ND; Etame, AB ATIM-18. A phase I trial of hypofractionated stereotactic irradiation (HFSRT) with pembrolizumab and bevacizumab in patients with recurrent high grade glioma (NCT02313272). Neurooncology., 2017, 19(suppl_6), pp. vi30-vi.
[110]
Ahluwalia, M.S.; Reardon, D.A.; Abad, A.P.; Curry, W.T.; Wong, E.T.; Belal, A. SurVaxM with standard therapy in newly diagnosed glioblastoma: Phase II trial update; American Society of Clinical Oncology, 2019.
[111]
Reardon, D; Nabors, B; Kumthekar, P; Badruddoja, M; Fink, K; Lieberman, F Atim-10. Phase 2 Trial Of Sl-701, A Novel Immunotherapy Comprised Of Synthetic Short Peptides Against Gbm Targets Il-13rα2, Epha2, And Survivin, In Adults With Second-line Recurrent Gbm. Neuro-Oncology, 2017, 19(suppl_6), vi28-vi.
[112]
Peereboom, D; Nabors, L; Kumthekar, P; Badruddoja, M; Fink, K; Lieberman, F 373O Results of phase II trial of SL-701, a novel immunotherapy targeting IL-13Ra2, EphA2, and survivin, in adults with second-line recurrent glioblastoma (GBM). Annals of Oncology., 2018, 29(suppl_8), mdy273-361.
[113]
Peereboom, D.M.; Nabors, L.B.; Kumthekar, P.; Badruddoja, M.A.; Fink, K.L.; Lieberman, F.S. Phase 2 trial of SL-701 in relapsed/refractory (r/r) glioblastoma (GBM): Correlation of immune response with longer-term survival; American Society of Clinical Oncology, 2018.
[114]
Wick, W.; Dietrich, P-Y.; Kuttruff, S.; Hilf, N.; Frenzel, K.; Admon, A. GAPVAC-101: First-in-human trial of a highly personalized peptide vaccination approach for patients with newly diagnosed glioblastoma; American Society of Clinical Oncology, 2018.
[121]
Keskin, D.B.; Anandappa, A.J.; Sun, J.; Tirosh, I.; Mathewson, N.D.; Li, S.; Oliveira, G.; Giobbie-Hurder, A.; Felt, K.; Gjini, E.; Shukla, S.A.; Hu, Z.; Li, L.; Le, P.M.; Allesøe, R.L.; Richman, A.R.; Kowalczyk, M.S.; Abdelrahman, S.; Geduldig, J.E.; Charbonneau, S.; Pelton, K.; Iorgulescu, J.B.; Elagina, L.; Zhang, W.; Olive, O.; McCluskey, C.; Olsen, L.R.; Stevens, J.; Lane, W.J.; Salazar, A.M.; Daley, H.; Wen, P.Y.; Chiocca, E.A.; Harden, M.; Lennon, N.J.; Gabriel, S.; Getz, G.; Lander, E.S.; Regev, A.; Ritz, J.; Neuberg, D.; Rodig, S.J.; Ligon, K.L.; Suvà, M.L.; Wucherpfennig, K.W.; Hacohen, N.; Fritsch, E.F.; Livak, K.J.; Ott, P.A.; Wu, C.J.; Reardon, D.A. Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial.
Nature, 2019,
565(7738), 234-239.
[
http://dx.doi.org/10.1038/s41586-018-0792-9] [PMID:
30568305]
[122]
Liau, L.M.; Ashkan, K.; Tran, D.D.; Campian, J.L.; Trusheim, J.E.; Cobbs, C.S.; Heth, J.A.; Salacz, M.; Taylor, S.; D’Andre, S.D.; Iwamoto, F.M.; Dropcho, E.J.; Moshel, Y.A.; Walter, K.A.; Pillainayagam, C.P.; Aiken, R.; Chaudhary, R.; Goldlust, S.A.; Bota, D.A.; Duic, P.; Grewal, J.; Elinzano, H.; Toms, S.A.; Lillehei, K.O.; Mikkelsen, T.; Walbert, T.; Abram, S.R.; Brenner, A.J.; Brem, S.; Ewend, M.G.; Khagi, S.; Portnow, J.; Kim, L.J.; Loudon, W.G.; Thompson, R.C.; Avigan, D.E.; Fink, K.L.; Geoffroy, F.J.; Lindhorst, S.; Lutzky, J.; Sloan, A.E.; Schackert, G.; Krex, D.; Meisel, H.J.; Wu, J.; Davis, R.P.; Duma, C.; Etame, A.B.; Mathieu, D.; Kesari, S.; Piccioni, D.; Westphal, M.; Baskin, D.S.; New, P.Z.; Lacroix, M.; May, S.A.; Pluard, T.J.; Tse, V.; Green, R.M.; Villano, J.L.; Pearlman, M.; Petrecca, K.; Schulder, M.; Taylor, L.P.; Maida, A.E.; Prins, R.M.; Cloughesy, T.F.; Mulholland, P.; Bosch, M.L. First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma.
J. Transl. Med., 2018,
16(1), 142.
[
http://dx.doi.org/10.1186/s12967-018-1507-6] [PMID:
29843811]