The following review article provides an overview of DHA chemistry, with specific confirmation based on major historical developments and progress mainly made over the last two decenniums. It is our hope this review serves as a valuable treasure to those interested in the 3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one (DHA) chemistry, and helps impact future advancements.
Keywords: 3-Acetyl-4-hydroxy-6-methyl-2H-pyran-2-one, DHA, synthesis, reactions, reaction mechanisms, biological activities.