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Letters in Organic Chemistry

Author(s): Mukesh C. Joshi*

DOI: 10.2174/1570178617999200619112911

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Synthesis and Characterization of Novel Phenoxy-Substituted Enediyne- Triazole Conjugates Using Click Chemistry

Page: [195 - 202] Pages: 8

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Abstract

Novel group of phenoxy-substituted enediyne-triazole conjugates were synthesized by Huisgen [3+2] cycloaddition reaction (Click chemistry) in aqueous media. It was observed that enediynes were stable in aqueous medium and open-air conditions.

Keywords: Enediyne, triazole, phenoxy-substituted enediyne-triazole conjugates, huisgen 1, 3-dipolar cycloaddition, click chemistry, aqueous medium.