One-Pot Multicomponent Synthesis of Imidazole Rings in Acidic Ionic Liquids: A Review

Cosmas    Chinweike    Eze; Mercy    Amarachi    Ezeokonkwo; Benjamin    Ebere    Ezema; Abraham    Efeturi    Onoabedje; Fidelia    Ngozika    Ibeanu; David    Izuchukwu    Ugwu; Leonard    Ebuka    Onyeyilim; James    Anayochwkwu    Ezugwu
Abstract

The design of the environmentally friendly approach to the synthesis of biologically important compounds without compromising the yield has been the focus of many chemists in recent years. The development of the one-pot synthesis of heterocycles in the presence of Ionic Liquids (ILs), used as both environmental media and catalysts, is efficient and environmentally sustainable. This review highlights the one-pot synthesis of imidazoles in acidic ILs in the past decade. Some reviews have been conducted on imidazoles, such as their pharmacological importance. Hence, we decided to focus on their synthesis in acidic ionic liquids, which the authors are not aware of any published literature.
Keywords: Environmental sustainability, imidazole, ionic liquids, multicomponent, one-pot synthesis, organic synthesis.
Graphical Abstract

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Cite As
Mini-Reviews in Organic Chemistry

One-Pot Multicomponent Synthesis of Imidazole Rings in Acidic Ionic Liquids: A Review

Abstract

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