Current Pharmaceutical Design

Author(s): Kuo-Chen Chou*

DOI: 10.2174/1381612825666191129164042

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An Insightful 10-year Recollection Since the Emergence of the 5-steps Rule

Page: [4223 - 4234] Pages: 12

  • * (Excluding Mailing and Handling)

Abstract

Objective: One of the most challenging and also the most difficult problems is how to formulate a biological sequence with a vector but considerably keep its sequence order information.

Methods: To address such a problem, the approach of Pseudo Amino Acid Components or PseAAC has been developed.

Results and Conclusion: It has become increasingly clear via the 10-year recollection that the aforementioned proposal has been indeed very powerful.

Keywords: PseAAC, PseKNC, 5-steps rule, byproducts, distorted key theory, biological sequence.