Abstract
Pathogenic bacteria constitute one of the most serious threats to human health. This has led
to the development of technologies for the rapid detection of bacteria. Bio-nanogold-based lateral flow
biosensors (LFBs) are a promising assay due to their low limit of detection, high sensitivity, good selectivity,
robustness, low cost, and quick assay performance ability. The aim of this review is to provide
a critical overview of the current variety of bio-nanogold LFBs and their targets, with a special focus on
whole-cell and DNA detection of pathogenic bacteria. The challenges of bio-nanogold-based LFBs in
improving their performance and accessibility are also comprehensively discussed.
Keywords:
Bio-nanogold, Lateral flow biosensor, Pathogenic bacteria, Rapid detection, LFBs, Nitrocellular membrane.
Graphical Abstract
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