[1]
Mortality, G.B.D. Causes of Death, C., Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet, 2015, 385(9963), 117-171.
[2]
Go, A.S.; Mozaffarian, D.; Roger, V.L.; Benjamin, E.J.; Berry, J.D.; Blaha, M.J.; Dai, S.; Ford, E.S.; Fox, C.S.; Franco, S.; Fullerton, H.J.; Gillespie, C.; Hailpern, S.M.; Heit, J.A.; Howard, V.J.; Huffman, M.D.; Judd, S.E.; Kissela, B.M.; Kittner, S.J.; Lackland, D.T.; Lichtman, J.H.; Lisabeth, L.D.; Mackey, R.H.; Magid, D.J.; Marcus, G.M.; Marelli, A.; Matchar, D.B.; McGuire, D.K.; Mohler, E.R., III; Moy, C.S.; Mussolino, M.E.; Neumar, R.W.; Nichol, G.; Pandey, D.K.; Paynter, N.P.; Reeves, M.J.; Sorlie, P.D.; Stein, J.; Towfighi, A.; Turan, T.N.; Virani, S.S.; Wong, N.D.; Woo, D.; Turner, M.B. American Heart Association Statistics, C.; Stroke Statistics, S., Heart disease and stroke statistics--2014 update: a report from the American Heart Association. Circulation, 2014, 129(3), e28-e292.
[3]
WHO World Health Organization: Global Status Report on Noncommunicable Diseases 2010., Geneva: World Health Organization.. 2011.
[4]
Ormazabal, V.; Nair, S.; Elfeky, O.; Aguayo, C.; Salomon, C.; Zuniga, F.A. Association between insulin resistance and the development of cardiovascular disease. Cardiovasc. Diabetol., 2018, 17(1), 122.
[5]
Ndisang, J.F.; Jadhav, A. Heme Arginate Therapy Enhanced Adiponectin and Atrial Natriuretic Peptide, but Abated Endothelin-1 with Attenuation of Kidney Histopathological Lesions in Mineralocorticoid-Induced Hypertension. J. Pharmacol. Exp. Ther., 2010, 334(1), 87-98.
[6]
Ndisang, J.F.; Jadhav, A. Hemin therapy suppresses inflammation and retroperitoneal adipocyte hypertrophy to improve glucose metabolism in obese rats co-morbid with insulin-resistant type-2 diabetes. Diabetes Obes. Metab., 2013, 15(11), 1029-1039.
[7]
Jadhav, A.; Ndisang, J.F. Treatment with heme arginate alleviates adipose tissue inflammation and improves insulin sensitivity and glucose metabolism in a rat model of Human primary aldosteronism. Free Radic. Biol. Med., 2012, 53(12), 2277-2286.
[8]
Salley, T.N.; Mishra, M.; Tiwari, S.; Jadhav, A.; Ndisang, J.F. The heme oxygenase system rescues hepatic deterioration in the condition of obesity co-morbid with type-2 diabetes. PLoS One, 2013, 8(11)e79270
[9]
Zhernakova, D.V.; Le, T.H.; Kurilshikov, A.; Atanasovska, B.; Bonder, M.J.; Sanna, S.; Claringbould, A.; Vosa, U.; Deelen, P. LifeLines cohort, s.; consortium, B.; Franke, L.; de Boer, R.A.; Kuipers, F.; Netea, M.G.; Hofker, M.H.; Wijmenga, C.; Zhernakova, A.; Fu, J., Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome. Nat. Genet., 2018.
[10]
Malik, V.S.; Willett, W.C.; Hu, F.B. Global obesity: trends, risk factors and policy implications. Nat. Rev. Endocrinol., 2013, 9(1), 13-27.
[11]
Costantino, S.; Mohammed, S.A.; Ambrosini, S.; Paneni, F. Epigenetic processing in cardiometabolic disease. Atherosclerosis, 2018.
[12]
Yamagishi, S.I.; Matsui, T. Pigment Epithelium-Derived Factor: A Novel Therapeutic Target for Cardiometabolic Diseases and Related Complications. Curr. Med. Chem., 2018, 25(13), 1480-1500.
[13]
Ndisang, J.F. Glomerular Endothelium and its Impact on Glomerular Filtration Barrier in Diabetes: Are the Gaps Still Illusive? Curr. Med. Chem., 2018, 25(13), 1525-1529.
[14]
Tarquini, R.; Pala, L.; Brancati, S.; Vannini, G.; De Cosmo, S.; Mazzoccoli, G.; Rotella, C.M. Clinical Approach to Diabetic Cardiomyopathy: A Review of Human Studies. Curr. Med. Chem., 2018, 25(13), 1510-1524.
[15]
Shinlapawittayatorn, K.; Chattipakorn, S.C.; Chattipakorn, N. The Influence of Obese Insulin-Resistance on the Outcome of the Ischemia/Reperfusion Insult to the Heart. Curr. Med. Chem., 2018, 25(13), 1501-1509.
[16]
Schreml, J.; Gouni-Berthold, I. Role of Anti-PCSK9 Antibodies in the Treatment of Patients with Statin Intolerance. Curr. Med. Chem., 2018, 25(13), 1538-1548.
[17]
Eleftheriadou, I.; Grigoropoulou, P.; Liberopoulos, E.; Liatis, S.; Kokkinos, A.; Tentolouris, N. Update on Cardiovascular Effects of Older and Newer Anti-diabetic Medications. Curr. Med. Chem., 2018, 25(13), 1549-1566.
[18]
Pittala, V.; Vanella, L.; Salerno, L.; Romeo, G.; Marrazzo, A.; Di Giacomo, C.; Sorrenti, V. Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions. Curr. Med. Chem., 2018, 25(13), 1577-1595.
[19]
Schmitz, J.; Gouni-Berthold, I. APOC-III Antisense Oligonucleotides: A New Option for the Treatment of Hypertriglyceridemia. Curr. Med. Chem., 2018, 25(13), 1567-1576.
[20]
Kramer, J.; Weidemann, F. Biomarkers for Diagnosing and Staging of Fabry Disease. Curr. Med. Chem., 2018, 25(13), 1530-1537.
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