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Mini-Reviews in Medicinal Chemistry

Author(s): Miao Li, Meng Pan, Chengzhong You and Jun Dou*

DOI: 10.2174/1389557519666190904141922

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The Therapeutic Potential of miR-7 in Cancers

Page: [1707 - 1716] Pages: 10

  • * (Excluding Mailing and Handling)

Abstract

MiRNAs play an important role in cancers. As a potent tumor suppressor, miRNA-7(miR-7) has been demonstrated to inhibit the diverse fundamental biological processes in multiple cancer types including initiation, growth and metastasis by targeting a number of molecules and signaling pathways. This current review summarizes and discusses the relationship between miR-7 and cancers and the therapeutic potential of miR-7 in cancers. It may provide new integrative understanding for future study on the role of miR-7 in cancers.

Keywords: miR-7, tumors, cancer cell signaling, therapy, RISC, ceRNA.

Graphical Abstract

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