Current Organic Chemistry

Author(s): Shigeki Kuroki, Kazuo Yamauchi, Isao Ando, Akira Shoji and Takuo Ozaki

DOI: 10.2174/1385272013374914

17O-Isotope Labeling and Hydrogen-Bonded Structure Investigation in Peptides and Polypeptides by Solid State 17O NMR

Page: [1001 - 1015] Pages: 15

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Abstract

Most recent research works on the hydrogen-bonded structure of solid 17O-labeled peptides and polypeptides by means of solid -state 17O NMR are presented. It has been demonstrated that 17O-labeling andsolid -state 17O NMR provide useful informations about the hydrogen-bonded structure between the amide oxygen and proton of peptides and polypeptides in the solid state, in addition to 1H, 13C and 15N techniques.