Search Result "Y253H"


In Silico Identification and Analysis of Drug Resistant Mutants of ABL Tyrosine Kinase Based on Detrimental Missense Mutations

Journal: Current Signal Transduction Therapy
Volume: 6 Issue: 3 Year: 2011 Page: 396-404
Author(s): R. Rajasekaran, C. George Priya Doss, G. Arun Prasad, Rao Sethumadhavan

Review Article

Insight to Pharmacokinetics of TKIs: Optimizing Practical Guidelines for Individualized Therapy

Journal: Current Drug Metabolism
Volume: 18 Issue: 3 Year: 2017 Page: 199-206
Author(s): Ruiqing Wang,Chaoqin Zhong,Chen Zhang,Mingqiang Hua,Daoxin Ma

Second-Generation Tyrosine Kinase Inhibitors as First-Line Treatment Strategy in Newly Diagnosed Chronic Phase Chronic Myeloid Leukemia Patients

Journal: Current Cancer Drug Targets
Volume: 12 Issue: 4 Year: 2012 Page: 391-401
Author(s): M. Breccia,G. Alimena

Basis for Resistance to Imatinib in 16 BCR-ABL Mutants as Determined Using Molecular Dynamics

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 4 Issue: 2 Year: 2009 Page: 164-173
Author(s): Tai-Sung Lee, Steven J. Potts, Maher Albitar

Nilotinib Therapy in Chronic Myelogenous Leukemia: The Strength of High Selectivity on BCR/ABL

Journal: Current Drug Targets
Volume: 10 Issue: 6 Year: 2009 Page: 530-536
Author(s): Massimo Breccia, Giuliana Alimena

New Insights into the Molecular Resistance Mechanisms of Chronic Myeloid Leukemia

Journal: Current Cancer Drug Targets
Volume: 16 Issue: 4 Year: 2016 Page: 323-345
Author(s): Rui Huang,Qian Kang,Huimin Liu,Yuhua Li

Molecular Dynamic Studies Unveil Potential Mechanisms of Resistance to Imatinib in BCR-ABL Mutants

Ebook: Topics in Anti-Cancer Research
Volume: 3 Year: 2014
Author(s): Tai-Sung Lee,Steven J. Potts,Maher Albitar
Doi: 10.2174/9781608059089114030011

Allosteric Inhibitors of Bcr-Abl: Towards Novel Myristate-Pocket Binders

Journal: Current Pharmaceutical Biotechnology
Volume: 14 Issue: 5 Year: 2013 Page: 477-487
Author(s): Marco Radi,Silvia Schenone,Maurizio Botta

Targeting Protein Multiple Conformations: A Structure-Based Strategy for Kinase Drug Design

Journal: Current Topics in Medicinal Chemistry
Volume: 7 Issue: 1 Year: 2007 Page: 1394-1407
Author(s): Liao Jie-Lou Jeffrey, Andrews C. Robert

The Emerging Role of Bcr-Abl-Induced Cystoskeletal Remodeling in Systemic Persistence of Leukemic Stem Cells

Journal: Current Drug Delivery
Volume: 11 Issue: 5 Year: 2014 Page: 582-591
Author(s): Adrian Bartos,Patrycja M. Dubielecka

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