Search Result "T-DM1"


Catabolic Fate and Pharmacokinetic Characterization of Trastuzumab Emtansine (T-DM1): an Emphasis on Preclinical and Clinical Catabolism

Journal: Current Drug Metabolism
Volume: 13 Issue: 7 Year: 2012 Page: 901-910
Author(s): Ben-Quan Shen,Daniela Bumbaca,Ola Saad,Qin Yue,Cinthia V. Pastuskovas,S. Cyrus Khojasteh,Jay Tibbitts,Surinder Kaur,Bei Wang,Yu-Waye Chu,Patricia M. LoRusso,Sandhya Girish

Non-Clinical Disposition and Metabolism of DM1, a Component of Trastuzumab Emtansine (T-DM1), in Sprague Dawley Rats

Journal: Drug Metabolism Letters
Volume: 9 Issue: 2 Year: 2015 Page: 119-131
Author(s): Ben-Quan Shen,Daniela Bumbaca,Qin Yue,Ola Saad,Jay Tibbitts,S. Cyrus Khojasteh,Sandhya Girish

Research Article

MMP7 Induces T-DM1 Resistance and Leads to the Poor Prognosis of Gastric Adenocarcinoma via a DKK1-Dependent Manner

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 18 Issue: 14 Year: 2018 Page: 2010-2016
Author(s): Hua Li,Xin Xu,Yang Liu,Shunle Li,Di Zhang,Xiaofen Meng,Le Lu,Yiming Li

Drug Interaction Potential of Trastuzumab Emtansine (T-DM1) Combined with Pertuzumab in Patients With HER2-Positive Metastatic Breast Cancer

Journal: Current Drug Metabolism
Volume: 13 Issue: 7 Year: 2012 Page: 911-922
Author(s): Dan Lu,Howard A. Burris III,Bei Wang,E. Claire Dees,Javier Cortes,Amita Joshi,Manish Gupta,Joo-Hee Yi,Yu-Waye Chu,Ted Shih,Liang Fang,Sandhya Girish

Review Article

T-DM1 in the Neo-Adjuvant Treatment of HER2-Positive Breast Cancer: Impact of the KRISTINE (TRIO-021) Trial

Journal: Reviews on Recent Clinical Trials
Volume: 12 Issue: 3 Year: 2017 Page: 216-222
Author(s): Alicia FC Okines

Understanding Trastuzumab Resistance in HER2 Positive Breast Cancer and Further Therapeutic Options

Journal: Current Cancer Therapy Reviews
Volume: 11 Issue: 4 Year: 2015 Page: 269-291
Author(s): Sangmee Bae,Sara Hurvitz

Anti-HER2 Therapy in Elderly Breast Cancer Patients

Journal: Reviews on Recent Clinical Trials
Volume: 9 Issue: 4 Year: 2014 Page: 263-266
Author(s): Masataka Sawaki

Review Article

Recent Advances in Antibody-Drug Conjugates for Breast Cancer Treatment

Journal: Current Medicinal Chemistry
Volume: 24 Issue: 23 Year: 2017 Page: 2505-2527
Author(s): Shanshan Deng,Zongtao Lin,Wei Li

Review Article

Toxicology of Trastuzumab: An Insight into Mechanisms of Cardiotoxicity

Journal: Current Cancer Drug Targets
Volume: 19 Issue: 5 Year: 2019 Page: 400-407
Author(s): Jie An,M. Saeed Sheikh

How New Drugs Are Developed: Drug Delivery

Ebook: Medicinal Chemistry - Fusion of Traditional and Western Medicine
Volume: 2 Year: 2014
Author(s): Robert E. Smith
Doi: 10.2174/9781608059744114020009

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