Current Molecular Pharmacology

Current Molecular Pharmacology aims to publish the latest developments in cellular and molecular pharmacology with a major emphasis on the mechanism of action of novel drugs under development, innovative pharmacological technologies, cell signaling, transduction pathway analysis, genomics, proteomics, and metabonomics applications ...read more

  • ISSN (Print): 1874-4672
  • ISSN (Online): 1874-4702
  • Issues: 17 , 2024
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Volume 17, 2024

Research Article open_access
Aloperine Alleviates Atherosclerosis by Inhibiting NLRP3 Inflammasome Activation in Macrophages and ApoE-/- Mice

Article ID: e18761429342447

Author(s): Zengxu Wang, Yuchuan Wang, Faisal Raza, Hajra Zafar, Chunling Guo, Weihua Sui, Yongchao Yang, Ran Li, Yifen Fang* and Bao Li*

DOI: 10.2174/0118761429342447241214044859

Published on: 14 January, 2025

Research Article open_access
Fenofibrate Inhibits LPS and Zymosan-induced Inflammatory Responses through Sonic Hedgehog in IMG Cells

Article ID: e18761429317532

Author(s): Yu-Wen Wang, Bor-Ren Huang, Dah-Yuu Lu*, Jin-Wun Chen, Vichuda Charoensaensuk, Liang-Yo Yang, Sheng-Wei Lai, Cheng-Fang Tsai* and Wei-Lan Yeh*

DOI: 10.2174/0118761429317532241017051135

Published on: 30 December, 2024

Research Article open_access
The Role of Dapagliflozin in the Modulation of Hypothermia and Renal Injury Caused by Septic Shock in Euglycemic and Hyperglycemic Rat Models

Article ID: e18761429329635

Author(s): Wael A. Alanazi*, Turki Alharbi, Khalid M. Bin Anzan, Musab K. Alyahiya, Doaa M. El-Nagar, Mohammed M. Alanazi, Mohammed M. Almutairi, Hussain N. Alhamami, Abdullah M. Albogami and Mohamed Mohany

DOI: 10.2174/0118761429329635241016054513

Published on: 12 December, 2024

Research Article open_access
Exploring the Pharmacological Mechanisms of P-hydroxylcinnamaldehyde for Treating Gastric Cancer: A Pharmacological Perspective with Experimental Confirmation

Article ID: e18761429322420

Author(s): Sumaya Fatima, Yanru Song, Zhe Zhang, Yuhui Fu, Ruinian Zhao, Khansa Malik and Lianmei Zhao*

DOI: 10.2174/0118761429322420241112051105

Published on: 10 December, 2024

Research Article open_access
Repair Effect of siRNA Double Silencing of the Novel Mechanically Sensitive Ion Channels Piezo1 and TRPV4 on an Osteoarthritis Rat Model

Article ID: e18761429317745

Author(s): Zhuqing Jia, Jibin Wang, Xiaofei LI, Qining Yang and Jianguo Han*

DOI: 10.2174/0118761429317745241017114020

Published on: 10 December, 2024

Research Article open_access
Neuroprotective Potential of Tanshinone-IIA in Mitigating Propionic Acidinduced Experimental Autism-like Behavioral and Neurochemical Alterations: Insights into c-JNK and p38MAPK Pathways

Article ID: e18761429326799

Author(s): Kajal Sherawat, Sidharth Mehan*, Zuber Khan, Aarti Tiwari, Ghanshyam Das Gupta and Acharan S. Narula

DOI: 10.2174/0118761429326799241121104310

Published on: 27 November, 2024

Research Article open_access
Evaluating the Anti-inflammatory Efficacy of a Novel Bipyrazole Derivative in Alleviating Symptoms of Experimental Colitis

Article ID: e18761429333261

Author(s): Yousra Bseiso, Omar Gammoh, Mohammad Alqudah, Sara Altaber, Esam Qnais, Mohammed Wedyan, Abdelrahim Alqudah* and Badriyah S. Alotaibi

DOI: 10.2174/0118761429333261241021034043

Published on: 26 November, 2024

Research Article open_access
Upregulation of LncRNA WT1-AS Inhibits Tumor Growth and Promotes Autophagy in Gastric Cancer via Suppression of PI3K/Akt/mTOR Pathway

Article ID: e18761429318398

Author(s): Xiaobei Zhang, Meng Jin, Xiaoying Yao, Jilan Liu, Yonghong Yang, Jian Huang, Guiyuan Jin, Shiqi Liu* and Baogui Zhang*

DOI: 10.2174/0118761429318398240918063450

Published on: 08 November, 2024

Corrigendum open_access
Corrigendum to: An Essential Role of c-Fos in Notch1-mediated Promotion of Proliferation of KSHV-Infected SH-SY5Y Cells

Article ID: e051124236081

Author(s): Huiling Xu, Jinghong Huang, Lixia Yao, Wenyi Gu, Aynisahan Ruzi, Yufei Ding, Ying Li, Weihua Liang, Jinfang Jiang, Zemin Pan, Dongdong Cao, Naiming Zhou*, Dongmei Li* and Jinli Zhang*

DOI: 10.2174/187446721701241105144436

Published on: 05 November, 2024

Research Article open_access
Mutations in Rv0678, Rv2535c, and Rv1979c Confer Resistance to Bedaquiline in Clinical Isolates of Mycobacterium Tuberculosis

Article ID: e18761429314641

Author(s): Khaoula Balgouthi*, Manaf AlMatar*, Hamza Saghrouchni, Osman Albarri and Isil Var

DOI: 10.2174/0118761429314641240815080447

Published on: 23 September, 2024

Research Article open_access
Short-term Uridine Treatment Alleviates Endoplasmic Reticulum Stress via Regulating Inflammation and Oxidative Stress in Lithium-Pilocarpine Model of Status Epilepticus

Article ID: e18761429315851

Author(s): Birnur Aydin, Cansu Koc, Mehmet Cansev and Tulin Alkan*

DOI: 10.2174/0118761429315851240909104349

Published on: 18 September, 2024

Corrigendum open_access
Corrigendum to: Progress of Angiogenesis Signal Pathway and Antiangiogenic Drugs in Nasopharyngeal Carcinoma

Article ID: e180924234131

Author(s): Yunzhi Zhu, Yi Hu, Chengsheng Yang, Shipu Huang, Jianping Wen*, Weiguo Huang* and Shengjun Xiao*

DOI: 10.2174/187446721701240918095836

Published on: 18 September, 2024

Corrigendum open_access
Corrigendum to: Bedaquiline in Drug-Resistant Tuberculosis: A Mini-Review

Article ID: e110924233920

Author(s): Baljinder Singh* and Charan Singh

DOI: 10.2174/187446721701240911110426

Published on: 11 September, 2024

Research Article open_access
Effect of Chrysin and Chrysin Nanocrystals on Chlorpyrifos-Induced Dysfunction of the Hypothalamic-Pituitary-Testicular Axis in Rats

Article ID: e18761429305457

Author(s): Tahereh Farkhondeh*, Babak Roshanravan, Fariborz Samini and Saeed Samarghandian*

DOI: 10.2174/0118761429305457240826093330

Published on: 02 September, 2024

Review Article open_access
Recent Advances in the Glycolytic Processes Linked to Tumor Metastasis

Article ID: e18761429308361

Author(s): Luo Qiong, Xiao Shuyao, Xu Shan, Fu Qian, Tan Jiaying, Xiao Yao and Ling Hui*

DOI: 10.2174/0118761429308361240823061634

Published on: 02 September, 2024

Review Article open_access
Mechanism, Potential, and Concerns of Immunotherapy for Hepatocellular Carcinoma and Liver Transplantation

Article ID: e18761429310703

Author(s): Bruno Sensi, Roberta Angelico*, Luca Toti, Luigi Eduardo Conte, Alessandro Coppola, Giuseppe Tisone and Tommaso Maria Manzia

DOI: 10.2174/0118761429310703240823045808

Published on: 02 September, 2024

Research Article open_access
Combined Phloretin and Human Platelet-rich Plasma Effectively Preserved Integrities of Brain Structure and Neurological Function in Rat after Traumatic Brain Damage

Article ID: e18761429316684

Author(s): Kun-Chen Lin, Kuan-Hung Chen, Pei-Lin Shao, Han-Tan Chai, Pei-Hsun Sung, John Y. Chiang, Sheung-Fat Ko and Hon-Kan Yip*

DOI: 10.2174/0118761429316684240816062458

Published on: 22 August, 2024

Review Article open_access
Adipose Tissue Dysfunction Following Trauma and Hypoxia Increases the Risk of Post-Surgical Adhesion: Potential for Therapeutic Interventions

Article ID: e18761429308567

Author(s): Rozita Khodashahi, Mahmoud Tavakkoli, Gorgon A Ferns, Leyla Feyzmohammadi, Amir Hossein Mirzaei, Mohsen Aliakbarian* and Mohammad-Hassan Arjmand*

DOI: 10.2174/0118761429308567240806111848

Published on: 13 August, 2024

Research Article open_access
Positive Regulation of Osteoblast Proliferation and Differentiation in MC3T3- E1 Cells by 7,3′,4′-Trimethoxyflavone

Article ID: e18761429305367

Author(s): Sharmeen Fayyaz, Atia tul-Wahab*, Bushra Taj and M. Iqbal Choudhary*

DOI: 10.2174/0118761429305367240725112731

Published on: 30 July, 2024

Mini-Review Article open_access
The Role of Local Angiotensin II/Angiotensin Type 1 Receptor in Endometriosis: A Potential Target for New Treatment Approaches

Article ID: e18761429315431

Author(s): Shirin Moazen and Mohammad-Hasan Arjmand*

DOI: 10.2174/0118761429315431240712100124

Published on: 22 July, 2024