Current Organic Synthesis

Author(s): Ping Wang, Ruimao Hua and Chao-Jun Li

DOI: 10.2174/157017941004150310102446

One-Pot Synthesis of 2,4,6-Triarylpyridines by the Oxidative Cyclocondensation of Benzaldehydes, Aromatic Alkynes and Ammonium Bifluoride

Page: [655 - 660] Pages: 6

  • * (Excluding Mailing and Handling)

Abstract

An efficient and one-pot synthesis of 2,4,6-triarylpyridines by palladium-catalyzed cyclocondensation of benzaldehydes, terminal aromatic alkynes and ammonium bifluoride in the presence of tert-butyl peroxide (TBP) as oxidant is developed.

Keywords: Aromatic alkyne, ammonium bifluoride; benzaldehyde, cyclocondensation, triarylpyridines.