Abstract

The common skin disorder known as facial hyperpigmentation is caused by an uneven distribution of melanin, which leaves the face with dark areas or spots. Numerous factors, such as inflammation, hormonal fluctuations, and sun exposure, might contribute to this condition. Chemical peels, laser therapy, and topical whitening agents are examples of traditional treatments for facial hyperpigmentation. On the other hand, these treatments may cause scarring, dryness, and inflammation of the skin. For the treatment of facial hyperpigmentation, nano-phytocosmeceuticals— cosmeceuticals containing nanoparticles generated from plant extracts—have shown great promise. Compared to traditional cosmeceuticals, these innovative formulations provide several benefits, such as better skin penetration, increased active ingredient bioavailability, and fewer side effects. Additionally, they have proved to be useful in lowering melanin synthesis and lightening hyperpigmented skin. Thus, an overview of the recent advances in the development and application of nanophytocosmeceuticals for facial hyperpigmentation, along with clinical studies and patents that have been granted have been provided in this article.

Graphical Abstract