Abstract

Background: Prostate cancer (PCa) is known as the fifth reason for cancer-related deaths and involves a considerable population of men globally. In PCa, pluriform neoplasm with different cancer patterns is formed. Metastases have a substantial role in disease mortality, and lung, liver, and bone are among the common organs for metastasis. In spite of multiple attempts by researchers, it has not been recommended a safe and suitable approach against PCa so far.

Results: Fortunately, herbal remedies have opened a novel window in order to treat several cancers, such as PCa; however, there are some barriers regarding this curative method, like low bioavailability and absorption and low water solubility. On the contrary, some nano-based formulations have revealed a potential ability to overcome these limitations, and it seems that the co-use of herbal products and nanoformulations provides a good opportunity for treating PCa.

Conclusion: In this study, we argued about the therapeutic aspects of some nanoformulations of popular herbal products, such as curcumin, quercetin, and resveratrol, against PCa.

Graphical Abstract